Peptisource

Klow 80mg（Blend）

TB4 is a synthetic peptide composed of 43 amino acids. Its sequence exhibits high homology with the active fragment of thymosin β4 (Tβ4), a multifunctional peptide naturally present in the human body that extensively participates in physiological processes such as cellular repair and inflammation regulation. The core mechanism of TB4 involves binding to actin on the cell surface to regulate cytoskeletal reorganization, thereby significantly promoting cell migration and tissue regeneration. In muscle, tendon, or ligament injury models, TB4 accelerates the aggregation of fibroblasts at the injury site, promotes the orderly arrangement of collagen fibers, shortens the healing cycle, and reduces the likelihood of scar tissue formation. TB4 induces angiogenesis by stimulating cytokine expression (e.g., vascular endothelial growth factor, VEGF), improving blood perfusion in injured areas to deliver ample oxygen and nutrients for tissue repair. It inhibits pro-inflammatory factor release (e.g., TNF-α, IL-6) and modulates macrophage polarization, thereby reducing post-injury inflammatory responses at the immunoregulatory level and preventing tissue damage from excessive inflammation.

Spec: Blend
Packaging: 1kits（10Vials）
$370USD
1

▎What is TB4?


TB4 is a synthetic peptide composed of 43 amino acids. Its sequence exhibits high homology with the active fragment of thymosin β4 (Tβ4), a multifunctional peptide naturally present in the human body that extensively participates in physiological processes such as cellular repair and inflammation regulation. The core mechanism of TB4 involves binding to actin on the cell surface to regulate cytoskeletal reorganization, thereby significantly promoting cell migration and tissue regeneration. In muscle, tendon, or ligament injury models, TB4 accelerates the aggregation of fibroblasts at the injury site, promotes the orderly arrangement of collagen fibers, shortens the healing cycle, and reduces the likelihood of scar tissue formation. TB4 induces angiogenesis by stimulating cytokine expression (e.g., vascular endothelial growth factor, VEGF), improving blood perfusion in injured areas to deliver ample oxygen and nutrients for tissue repair. It inhibits pro-inflammatory factor release (e.g., TNF-α, IL-6) and modulates macrophage polarization, thereby reducing post-injury inflammatory responses at the immunoregulatory level and preventing tissue damage from excessive inflammation.